IDEA #98EW2J Biotechnological Yeast-based Production Of Vitamin B2 (riboflavin)

Areas of Application Vitamin B2 produced by microbial fermentation can be used for human and animal nutrition, as a food colorant, as well as a medicine Specifi cation Ribofl avin synthesizing strains have been constructed using advanced metabolic engineering methods. Medium composition and cultivation conditions have been optimized to maximize the yield of target product. A laboratory procedure for vitamin B2 production has been developed IPR Protection IPR3, IPR5 Advantages There are no counterparts in Ukraine. The constructed strains are characterized by effi cient ribofl avin production. The main advantage of these strains is a higher genetic stability relative as compared with available ribofl avin producers. Biotechnological ribofl avin production reduces energy consumption and chemical pollution of environment Stage of Development. Suggestions for Commercialization IRL3, TRL4 The ribofl avin producer cultivation is scaled and a technology for commercial production of vitamin B2 is developed. The constructed ribofl avin overproducing strains and the developed technology can saturate the Ukrainian market with the product. The Institute is seeking a company interested in strain commercialization