Areas of Application
The affinity medium based on oriented
immobilized recombinant protein A
Staphylococcus aureus can be used at research
institutes and diagnostic labs for purification
of monoclonal and polyclonal antibodies
from ascites, serum, and cell culture
supernatants; for fractionation
of IgG into subclasses; and for isolation
of antibody/antigen complexes
in immunoprecipitation experiments
Specification
The affinity sorbent based on microcrystalline
cellulose СС31 with immobilized recombinant
protein А Staphylococcus aureus in the form
of 50% suspension in 20% ethanol;
particle size: ~60—75 μm;
ligand density: ~1.5—2.0 mg ligand/ml sorbent
Advantages
The use of affi nity medium enables
a single-stage purifi cation of antibodies.
The cost of proposed affi nity medium
is lower as compared with that of the analogs
IPR Protection
IPR1, IPR2
Stage of Development.
Suggestion for Commercialization
IRL3, TRL3
Affinity medium sample and protocol
for antibody purifi cation provided upon
request. After tests, the offering
can be proposed to manufacturers
and suppliers of laboratory equipment,
reagents, and materials
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